Clean Up Computer

Not able to open any programs after using registry cleaner?

I used a windows registry cleaner and ticked the boxes for all file extensions. Now I am not able to open any file. None of the file extensions are opening although the system starts normally. When I press CTRL+ALD+DLT, only the explorer is running. How do I restore my system. Please help me.
I am not able to open System restore from System tools as the lnk is not opening.

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