Clean Up Computer

what is the best way to get rid of the Vundo virus? I scan my computer, says it is clean but keeps comin back?

I scan with both AVG & Malware and they both say they have cleaned,healed and moved to virus vault this infection but it keeps coming back. It has disabled my MIscrosoft security center for any updates and its seems to be in the registry. ANY HELP WOULD BE GREATLY APPREICATED–GOING BONKERS!!!!!

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