Clean Up Computer

How to clean up/remove the Web Client/Publisher Temporary Files accumulated on the diskC of a computer?

What are Web Client/Publisher Temporary files?
While cleaning up the disk C for better space under the performance and maintenance programme of the control panel, the web Client/Publisher temporary files are not getting deleted/erased, inspite of the computer saying that they are not necessary and can be safely removed, and even after putting a check mark in the box. Why? And how to delete them?

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