He has a lot of nonsense on his laptop and i have already installed a pestpatrol and an antivirus and ran them both so i have all pests and viruses off. how do i clean up his desktop from all the icons and make it look and run like a well maintained computer??

My computer seems to have contracted spyware, specifically WinFixer. I have run Adaware, SpyBot S&D, AVG, and PestPatrol and have had no luck in getting rid of it. Any suggestions would be greatly appriciated.