I heard that if you download an antivirus program and another antivirus program while the old anitvirus program is still installed, your computer would be all messed up and glitchy. Right Now I have Avira, but Avira doesn't fix the RUNDLL Error, and I look at yahoo answer, nothing work, and youtube too.

So if I download a Registry Cleaner and installed it while Avira is installed, would my computer be messed up? What happen if I download a spyware, malware, registry cleaner, and an antivirus program? What would happen with my computer with all these programs? Since Avira doesn't protect spyware, malware, and doesn't do a registry cleaner.
What would happen if I download with anything in any particular order.

I downloaded what I thought was a completely free registry cleaner last night… turns out it was a trial. I don't have any money to spend, and I have enough crap wrong with my computer already, so I'm looking for a FREE and TRUSTWORTHY registry cleaner. Any *good* free anti-spyware/malware/virus programs are appreciated as well.

what is the most efficient way to clean up computer systems from viruses, spyWare, malware,root-kits ,trojan horses, and any adware ?
in a free or cheap way?
plus I might be doing this for other people so if there is any suggestions on how to do that on multiple pcs.
I would appreciate it if you explain in step by step process?
Please provide details as much as possible.
Thank You In Advance.